Melanotan I (afamelanotide) is an α-MSH analogue studied as a melanocortin-1 receptor agonist in research models of melanogenesis and photoprotective pigmentation pathways.
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Melanogenesis models: Studied for α-MSH / MC1R-driven melanin-synthesis pathways.
Photoprotection research: Used to investigate UV-protective pigmentation responses.
Receptor selectivity: Probes MC1R signalling with narrower activity than Melanotan II.